Analytical Biases Associated with GC-Content in Molecular Evolution

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Analytical Biases Associated with GC-Content in Molecular Evolution

Molecular evolution is being revolutionized by high-throughput sequencing allowing an increased amount of genome-wide data available for multiple species. While base composition summarized by GC-content is one of the first metrics measured in genomes, its genomic distribution is a frequently neglected feature in downstream analyses based on DNA sequence comparisons. Here, we show how base compo...

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ژورنال

عنوان ژورنال: Frontiers in Genetics

سال: 2017

ISSN: 1664-8021

DOI: 10.3389/fgene.2017.00016